HitPredict

Interactor 1: PTN5 (P54829)
Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP)
Gene: PTPN5

Interactor 2: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27457929
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0030054 - cell junction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 565 Hs			1 724
+	Mm
		873172 PTN5_MOUSE (25-565): 0: 746: 90.02		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Rn
		677764 PTN5_RAT (197-565): 0: 519: 94.85		DLG4_RAT (1-724): 0: 668: 99.86
+	Rn
		677796 Q66HJ7_RAT (111-564): 1.35e-114: 360: 24.64		DLG4_RAT (1-724): 0: 668: 99.86
+	Rn
		94281 F1LXJ9_RAT (296-559): 6.85e-67: 238: 27.27		DLG4_RAT (1-724): 0: 668: 99.86
+	Hs
		617101 PTPRG_HUMAN (296-561): 4.35e-52: 194: 24.37		DLG4_HUMAN (1-724): 0: 667: 100.00
+	Rn
		677786 PTPRZ_RAT (325-552): 1.03e-21: 102: 29.83		DLG4_RAT (1-724): 0: 668: 99.86
+	Hs
		617048 PTPRE_HUMAN (296-564): 2.83e-100: 320: 31.67		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93
+	Rn
		94287 F1LXJ9_RAT (296-559): 6.85e-67: 238: 27.27		CSKP_RAT (6-200): 2.45e-19: 95.2: 14.80
+	Rn
		1143999 PTPRZ_RAT (325-552): 1.03e-21: 102: 29.83		DLG2_RAT (225-474): 1.48e-18: 92.5: 21.09