HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 360
+	Hs
		882083 TCPG_HUMAN (14-540): 0: 574: 33.15		SEH1_HUMAN (1-360): 2.39e-78: 246: 100.00
+	Hs
		1388900 TCPH_HUMAN (12-539): 0: 572: 29.64		SEH1_HUMAN (1-360): 2.39e-78: 246: 100.00
+	Hs
		876070 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1A_HUMAN (98-354): 2.44e-50: 175: 13.62
+	Hs
		882038 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1A_HUMAN (98-354): 2.44e-50: 175: 13.62
+	Hs
		1334162 TCPH_HUMAN (12-539): 0: 572: 29.64		POC1A_HUMAN (98-354): 2.44e-50: 175: 13.62
+	Hs
		876081 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1B_HUMAN (202-357): 2.98e-25: 107: 10.81
+	Hs
		882014 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5B_HUMAN (78-360): 1.43e-49: 170: 17.31
+	Hs
		882075 TCPG_HUMAN (14-540): 0: 574: 33.15		FBXW7_HUMAN (94-360): 2.63e-46: 169: 10.82
+	Hs
		1291941 TCPH_HUMAN (12-539): 0: 572: 29.64		WDR5B_HUMAN (78-360): 1.43e-49: 170: 17.31
+	Hs
		845257 TCPG_HUMAN (14-540): 0: 574: 33.15		LIS1_HUMAN (91-357): 4.5e-46: 163: 15.68
+	Hs
		302777 TCPE_HUMAN (1-541): 0: 637: 100.00		CIAO1_HUMAN (57-321): 2.69e-22: 98: 20.71
+	Hs
		876112 TCPE_HUMAN (1-541): 0: 637: 100.00		SNR40_HUMAN (3-140): 1.03e-21: 96.4: 18.88
+	Hs
		876199 TCPE_HUMAN (1-541): 0: 637: 100.00		NLE1_HUMAN (252-357): 2.69e-20: 93.7: 16.04
+	Hs
		875898 TCPE_HUMAN (1-541): 0: 637: 100.00		WDR5_HUMAN (253-360): 1.76e-17: 84.1: 18.52
+	Hs
		875885 TCPE_HUMAN (1-541): 0: 637: 100.00		SEC13_HUMAN (216-345): 2.33e-17: 83.7: 18.94
+	Hs
		882051 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1B_HUMAN (202-357): 2.98e-25: 107: 10.81
+	Hs
		302780 TCPG_HUMAN (14-540): 0: 574: 33.15		CIAO1_HUMAN (57-321): 2.69e-22: 98: 20.71
+	Hs
		302937 TCPH_HUMAN (12-539): 0: 572: 29.64		CIAO1_HUMAN (57-321): 2.69e-22: 98: 20.71
+	Hs
		881861 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5_HUMAN (253-360): 1.76e-17: 84.1: 18.52
+	Hs
		965190 TCPH_HUMAN (12-539): 0: 572: 29.64		WDR5_HUMAN (253-360): 1.76e-17: 84.1: 18.52