Protein: SEC13
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)

Gene: SEC13
Organism: Homo sapiens
Interactions: 195
UniProt ID: P55735

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

323855

SC31A
Protein transport protein Sec31A

9

19

Small-scale

0.981

High

938231

WDR59
GATOR2 complex protein WDR59

7

20

Small-scale

0.966

High

938274

WDR24
GATOR2 complex protein WDR24

7

20

Small-scale

0.966

High

938245

NUP37
Nucleoporin Nup37

7

16

Small-scale

0.965

High

938297

MIOS
GATOR2 complex protein MIOS

6

20

Small-scale

0.950

High

938279

NUP85
Nuclear pore complex protein Nup85

6

5

Small-scale

0.947

High

938267

SC16B
Protein transport protein Sec16B

5

13

High-throughput

0.938

High

174995

SC16A
Protein transport protein Sec16A

5

17

Small-scale

0.930

High

938263

SEH1
Nucleoporin SEH1

5

16

Small-scale

0.929

High

915933

NUP98
Nuclear pore complex protein Nup98-Nup96

5

20

High-throughput

0.927

High

938244

NUP43
Nucleoporin Nup43

4

18

High-throughput

0.903

High

938192

SEC13
Protein SEC13 homolog

2

16

Small-scale

0.815

High

938259

PPWD1
Peptidylprolyl isomerase domain and WD repeat-containing protein 1

2

17

High-throughput

0.811

High

938294

SAR1A
Small COPII coat GTPase SAR1A

2

7

High-throughput

0.789

High

938229

A16L1
Autophagy-related protein 16-1

2

17

High-throughput

0.754

High

938196

NU107
Nuclear pore complex protein Nup107

9

6

Small-scale

0.753

High

938210

NU160
Nuclear pore complex protein Nup160

5

3

Small-scale

0.718

High

938250

NU133
Nuclear pore complex protein Nup133

5

4

Small-scale

0.718

High

938237

AGRF5
Adhesion G protein-coupled receptor F5

2

2

High-throughput

0.700

High

876793

KC1A
Casein kinase I isoform alpha

4

9

High-throughput

0.699

High

840869

TEC
Tyrosine-protein kinase Tec

1

2

High-throughput

0.691

High

875885

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.691

High

938278

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

19

High-throughput

0.691

High

136674

TRAF5
TNF receptor-associated factor 5

3

10

High-throughput

0.675

High

189482

STX7
Syntaxin-7

3

1

High-throughput

0.667

High

539984

BCR
Breakpoint cluster region protein

3

10

High-throughput

0.667

High

938197

SESN2
Sestrin-2

3

1

High-throughput

0.667

High

938255

TFG
Protein TFG

3

12

High-throughput

0.667

High

938262

SPDLY
Protein Spindly

3

13

High-throughput

0.667

High

97017

E9PK14
Protein transport protein sec16

1

6

High-throughput

0.665

High

938290

LT4R2
Leukotriene B4 receptor 2

1

0

High-throughput

0.663

High

938224

KLH12
Kelch-like protein 12

3

2

Small-scale

0.656

High

938284

HPLN2
Hyaluronan and proteoglycan link protein 2

2

0

High-throughput

0.655

High

276450

PDCD6
Programmed cell death protein 6

2

1

Small-scale

0.639

High

938209

ACY1
Aminoacylase-1

3

0

High-throughput

0.638

High

938240

PR38A
Pre-mRNA-splicing factor 38A

3

0

High-throughput

0.638

High

483316

CLCB
Clathrin light chain B

2

2

High-throughput

0.628

High

885732

KC1E
Casein kinase I isoform epsilon

2

12

High-throughput

0.628

High

843424

HD
Huntingtin

2

1

High-throughput

0.621

High

315339

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.618

High

938201

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.618

High

938202

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.618

High

938292

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.618

High

938293

ANLN
Anillin

1

3

High-throughput

0.618

High

938308

SAR1B
Small COPII coat GTPase SAR1B

1

8

High-throughput

0.618

High

338447

SC24B
Protein transport protein Sec24B

2

10

Small-scale

0.611

High

938213

CUL3
Cullin-3

2

20

High-throughput

0.611

High

938291

MED4
Mediator of RNA polymerase II transcription subunit 4

2

2

High-throughput

0.611

High

938303

DICER
Endoribonuclease Dicer

1

13

Small-scale

0.575

High

179860

BET1
BET1 homolog

2

2

High-throughput

0.571

High

218016

TGON2
Trans-Golgi network integral membrane protein 2

2

5

High-throughput

0.571

High

385598

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

10

High-throughput

0.571

High

395766

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

938218

EEA1
Early endosome antigen 1

2

13

High-throughput

0.571

High

938236

DOCK3
Dedicator of cytokinesis protein 3

2

3

High-throughput

0.571

High

938254

ESR2
Estrogen receptor beta

2

17

High-throughput

0.571

High

938223

QRIC1
Transcriptional regulator QRICH1

2

9

High-throughput

0.558

High

363044

EGFR
Epidermal growth factor receptor

1

2

Small-scale

0.554

High

710694

EPHA8
Ephrin type-A receptor 8

1

4

High-throughput

0.553

High

938233

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

938285

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.553

High

415464

HSPB1
Heat shock protein beta-1

1

8

High-throughput

0.541

High

171687

GAK
Cyclin-G-associated kinase

1

7

High-throughput

0.536

High

483058

CLCA
Clathrin light chain A

1

2

High-throughput

0.536

High

529435

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.536

High

637416

FLNA
Filamin-A

1

12

High-throughput

0.536

High

650667

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

16

High-throughput

0.536

High

877076

KC1D
Casein kinase I isoform delta

1

10

High-throughput

0.536

High

938193

AP1S2
AP-1 complex subunit sigma-2

1

3

High-throughput

0.536

High

938198

RAB14
Ras-related protein Rab-14

1

5

High-throughput

0.536

High

938205

CLH1
Clathrin heavy chain 1

1

6

High-throughput

0.536

High

938212

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

4

High-throughput

0.536

High

938215

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.536

High

938219

SC23A
Protein transport protein Sec23A

1

10

High-throughput

0.536

High

938227

SZT2
KICSTOR complex protein SZT2

1

1

Small-scale

0.536

High

938253

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

1

High-throughput

0.536

High

938265

AURKB
Aurora kinase B

1

7

High-throughput

0.536

High

938268

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.536

High

938280

YJU2
Splicing factor YJU2

1

1

High-throughput

0.536

High

938282

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

4

High-throughput

0.536

High

938299

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

938301

TPC1
Two pore channel protein 1

1

1

High-throughput

0.536

High

938306

PKHM1
Pleckstrin homology domain-containing family M member 1

1

3

Small-scale

0.536

High

938309

S23IP
SEC23-interacting protein

1

8

High-throughput

0.536

High

477134

5HT1A
5-hydroxytryptamine receptor 1A

1

0

Small-scale

0.517

High

938270

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.517

High

847976

RAD52
DNA repair protein RAD52 homolog

1

0

Small-scale

0.513

High

938247

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.513

High

938264

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.513

High

789084

NUP62
Nuclear pore glycoprotein p62

1

19

Small-scale

0.506

High

339696

KLF8
Krueppel-like factor 8

1

18

High-throughput

0.500

High

851479

GATA4
Transcription factor GATA-4

1

4

High-throughput

0.500

High

938276

ELF4
ETS-related transcription factor Elf-4

1

14

High-throughput

0.500

High

176393

ZBTB5
Zinc finger and BTB domain-containing protein 5

1

2

High-throughput

0.489

High

938232

FA83H
Protein FAM83H

1

1

High-throughput

0.489

High

938203

RB11A
Ras-related protein Rab-11A

1

3

Small-scale

0.481

High

128899

MEN1
Menin

1

3

High-throughput

0.479

High

172623

XPO1
Exportin-1

1

10

High-throughput

0.479

High

241216

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

247770

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

296473

STAM2
Signal transducing adapter molecule 2

1

2

Small-scale

0.479

High

319089

SC24D
Protein transport protein Sec24D

1

10

Small-scale

0.479

High

324677

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

330794

KI20A
Kinesin-like protein KIF20A

1

12

High-throughput

0.479

High

338305

SC24A
Protein transport protein Sec24A

1

10

Small-scale

0.479

High

347604

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

375326

RASK
GTPase KRas

1

6

High-throughput

0.479

High

379967

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.479

High

400548

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

405945

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

413492

P53
Cellular tumor antigen p53

1

6

Small-scale

0.479

High

519883

ANDR
Androgen receptor

1

17

High-throughput

0.479

High

540381

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

Small-scale

0.479

High

588320

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

606507

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

611054

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

659416

CRCM
Colorectal mutant cancer protein

1

4

High-throughput

0.479

High

695047

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

764586

CTNB1
Catenin beta-1

1

11

High-throughput

0.479

High

767811

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

774950

FUS
RNA-binding protein FUS

1

15

High-throughput

0.479

High

798905

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

832964

ETV6
Transcription factor ETV6

1

14

High-throughput

0.479

High

851733

NKX21
Homeobox protein Nkx-2.1

1

6

High-throughput

0.479

High

853773

MK09
Mitogen-activated protein kinase 9

1

5

High-throughput

0.479

High

887872

MCM2
DNA replication licensing factor MCM2

1

9

High-throughput

0.479

High

919838

PLK1
Serine/threonine-protein kinase PLK1

1

8

High-throughput

0.479

High

925703

SC24C
Protein transport protein Sec24C

1

10

Small-scale

0.479

High

934332

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.479

High

938194

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

938199

WDR5
WD repeat-containing protein 5

1

17

High-throughput

0.479

High

938200

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

9

High-throughput

0.479

High

938206

HSF1
Heat shock factor protein 1

1

4

High-throughput

0.479

High

938207

EWS
RNA-binding protein EWS

1

13

High-throughput

0.479

High

938214

CUL4A
Cullin-4A

1

20

High-throughput

0.479

High

938216

CUL7
Cullin-7

1

5

High-throughput

0.479

High

938220

SC23B
Protein transport protein Sec23B

1

10

Small-scale

0.479

High

938221

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

938222

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

938225

AKIR2
Akirin-2

1

1

Small-scale

0.479

High

938230

RNF43
E3 ubiquitin-protein ligase RNF43

1

4

High-throughput

0.479

High

938234

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

938235

SKA3
Spindle and kinetochore-associated protein 3

1

1

Small-scale

0.479

High

938239

RHG18
Rho GTPase-activating protein 18

1

4

High-throughput

0.479

High

938241

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

938242

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

938251

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

938256

HDAC2
Histone deacetylase 2

1

10

High-throughput

0.479

High

938257

STAM1
Signal transducing adapter molecule 1

1

1

Small-scale

0.479

High

938269

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

938272

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

938275

RING2
E3 ubiquitin-protein ligase RING2

1

15

High-throughput

0.479

High

938286

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

1

High-throughput

0.479

High

938287

ECT2
Protein ECT2

1

14

High-throughput

0.479

High

938288

AKIR1
Akirin-1

1

1

Small-scale

0.479

High

938289

NMRL1
NmrA-like family domain-containing protein 1

1

3

High-throughput

0.479

High

938295

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.479

High

938296

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

938298

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

10

High-throughput

0.479

High

938300

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

938302

FAF1
FAS-associated factor 1

1

5

High-throughput

0.479

High

938307

ARI1
E3 ubiquitin-protein ligase ARIH1

1

12

High-throughput

0.479

High

76191

B4DHB6
Cilia- and flagella-associated protein 43

1

18

High-throughput

0.470

High

938204

CCNA1
Cyclin-A1

1

0

High-throughput

0.458

High

938217

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

938226

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

938246

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

938248

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

938252

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

938277

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

938266

P121A
Nuclear envelope pore membrane protein POM 121

1

20

Small-scale

0.457

High

776038

SOX5
Transcription factor SOX-5

1

16

High-throughput

0.457

High

938281

KLF16
Krueppel-like factor 16

1

14

High-throughput

0.457

High

563487

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

881502

CDK8
Cyclin-dependent kinase 8

1

15

High-throughput

0.445

High

938211

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.445

High

938271

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

3

High-throughput

0.445

High

938273

NUDC1
NudC domain-containing protein 1

1

2

High-throughput

0.445

High

938305

ST38L
Serine/threonine-protein kinase 38-like

1

6

High-throughput

0.445

High

938243

CFA43
Cilia- and flagella-associated protein 43

1

7

High-throughput

0.439

High

192568

NUP42
Nucleoporin NUP42

1

0

Small-scale

0.438

High

293434

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

938208

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

938228

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.426

High

938249

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

938304

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

989

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.407

High

254909

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

938195

CLD12
Claudin-12

1

0

High-throughput

0.282

High

938260

FWCH2
FLYWCH family member 2

1

0

High-throughput

0.279

Low

938261

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.268

Low

938238

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

938258

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

938283

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025