HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23750010
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045296 - cadherin binding GO:0051015 - actin filament binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 649
+	Hs
		876440 AFAD_HUMAN (1-1824): 0: 1279: 100.00		MINK1_HUMAN (185-545): 2.22e-27: 120: 13.66
+	Hs
		297818 AFAD_HUMAN (1-1824): 0: 1279: 100.00		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		876457 AFAD_HUMAN (1-1824): 0: 1279: 100.00		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Hs
		1085096 MYO5B_HUMAN (102-939): 4.92e-118: 416: 14.72		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		1066178 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		1085094 NEB1_HUMAN (1002-1092): 1.04e-19: 98.7: 40.00		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		1085071 MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Mm
		1143537 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		DREB_MOUSE (1-649): 1.02e-75: 258: 80.45
+	Hs
		1085107 MYO5A_HUMAN (1369-1800): 2.36e-11: 71.5: 10.74		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Dm
		113616 M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95		DBNL_DROME (3-462): 7.49e-62: 216: 22.85
+	Hs
		1066369 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		RB12B_HUMAN (173-626): 1.39e-17: 89.1: 13.95
+	Hs
		1066964 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		PCLO_HUMAN (135-639): 1.66e-09: 63.7: 9.64
+	Hs
		1066313 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MICA3_HUMAN (205-642): 2.69e-09: 62.9: 11.11
+	Mm
		1143433 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		SYNJ1_MOUSE (126-647): 1.58e-41: 164: 10.90
+	Mm
		88458 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		D3Z656_MOUSE (126-647): 7.39e-40: 159: 10.52
+	Dm
		113219 M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95		Q7KU92_DROME (157-646): 6.28e-35: 144: 13.88
+	Mm
		581224 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		NFH_MOUSE (148-646): 1.45e-22: 105: 11.62
+	Hs
		1068614 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		CTTB2_HUMAN (131-644): 3.31e-33: 139: 14.55
+	Mm
		1143531 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		MINK1_MOUSE (185-545): 2.22e-09: 62.8: 14.25