Interactor 1: MP2K1 (P31938)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: Map2k1

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 28706196
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Pkinase~Ras
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0030425 - dendrite
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 393
Mm

1 1186
+ Hs
+ Dm
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024