HitPredict

Interactor 1: ELL (P55199)
RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)
Gene: ELL

Interactor 2: EAF1 (Q96JC9)
ELL-associated factor 1
Gene: EAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	32152128, 36036574, 26186194, 28514442, 11418481, 33961781, 21729782
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	EAF~ELL
Common GO terms	GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0008023 - transcription elongation factor complex GO:0015030 - Cajal body GO:0016604 - nuclear body and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 268
+	Hs
		876658 ELL_HUMAN (1-621): 0: 833: 100.00		EAF2_HUMAN (1-268): 2.26e-102: 300: 54.35
+	Hs
		130169 ELL2_HUMAN (2-620): 0: 772: 45.76		EAF1_HUMAN (1-268): 3.16e-103: 303: 100.00
+	Hs
		130168 ELL2_HUMAN (2-620): 0: 772: 45.76		EAF2_HUMAN (1-268): 2.26e-102: 300: 54.35
+	Hs
		1295112 ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53		EAF1_HUMAN (1-268): 3.16e-103: 303: 100.00
+	Hs
		1286797 ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53		EAF2_HUMAN (1-268): 2.26e-102: 300: 54.35