HitPredict

Interactor 1: NP1L1 (P55209)
Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP)
Gene: NAP1L1

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 130
+	Hs
		391616 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470307 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		876804 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		555373 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		391863 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470518 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		1087091 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Dm
		950430 Q24150_DROME (10-391): 3.64e-120: 354: 44.16		H2A_DROME (17-122): 2.2e-58: 178: 93.40
+	Dm
		950446 Q9W1G7_DROME (10-391): 4.29e-120: 354: 44.16		H2A_DROME (17-122): 2.2e-58: 178: 93.40
+	Sc
		392309 NAP1_YEAST (16-390): 4.36e-102: 310: 30.61		H2A2_YEAST (16-121): 8.79e-53: 164: 83.96
+	Ce
		452190 Q19007_CAEEL (51-371): 1.19e-88: 272: 40.62		H2A_CAEEL (17-125): 7.23e-56: 171: 90.83
+	Hs
		391771 TSYL5_HUMAN (18-357): 2.73e-64: 212: 15.91		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		391896 TSYL1_HUMAN (71-343): 7.16e-63: 209: 18.32		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		555417 SET_HUMAN (62-343): 2.66e-57: 190: 20.28		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94