Interactor 1: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1

Interactor 2: DSG2 (Q14126)
Desmoglein-2 (Cadherin family member 5) (HDGC)
Gene: DSG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 18942891
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0030054 - cell junction
GO:0043066 - negative regulation of apoptotic process
GO:0098609 - cell-cell adhesion
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 467
Hs

1 1118
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025