HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

The method score is based on:

Property	Details
Experiments	27153538, 20946988, 10966108
Identification Methods	affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0000785 - chromatin GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm and 10 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0035267 - NuA4 histone acetyltransferase complex GO:0042981 - regulation of apoptotic process GO:0045663 - positive regulation of myoblast differentiation GO:0045893 - positive regulation of DNA-templated transcription GO:0051726 - regulation of cell cycle GO:1905168 - positive regulation of double-strand break repair via homologous recombination GO:2000779 - regulation of double-strand break repair
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1	375
Hs

1	513

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024