HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0045335 - phagocytic vesicle and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 218
+	Hs
		564470 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		1079966 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		925305 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		951020 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		900511 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		913995 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		918948 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		918847 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		893868 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		893872 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		918849 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		900355 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		925600 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Hs
		894409 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Hs
		900882 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Hs
		895271 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895028 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		893849 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895037 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895022 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56