HitPredict

Interactor 1: CXCR4 (P61073)
C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184)
Gene: CXCR4

Interactor 2: SGMR1 (Q99720)
Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)
Gene: SIGMAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031410 - cytoplasmic vesicle GO:0070161 - anchoring junction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 352 Hs			1 223
+	Hs
		1031059 GPR17_HUMAN (23-346): 8.96e-81: 252: 24.92		SGMR1_HUMAN (1-223): 8.23e-130: 366: 100.00
+	Hs
		686730 CCR1_HUMAN (25-350): 5.5e-76: 239: 31.21		SGMR1_HUMAN (1-223): 8.23e-130: 366: 100.00
+	Hs
		723387 APJ_HUMAN (14-345): 1.96e-69: 223: 25.64		SGMR1_HUMAN (1-223): 8.23e-130: 366: 100.00
+	Hs
		723092 OPRM_HUMAN (3-342): 8.92e-68: 220: 22.22		SGMR1_HUMAN (1-223): 8.23e-130: 366: 100.00
+	Hs
		134401 ACKR2_HUMAN (8-320): 1.39e-46: 164: 32.81		SGMR1_HUMAN (1-223): 8.23e-130: 366: 100.00
+	Hs
		626580 FPR2_HUMAN (38-325): 2.73e-40: 146: 32.79		SGMR1_HUMAN (1-223): 8.23e-130: 366: 100.00