HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: TRI50 (Q86XT4)
E3 ubiquitin-protein ligase TRIM50 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM50) (Tripartite motif-containing protein 50)
Gene: TRIM50

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 487
+	Hs
		584907 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RO52_HUMAN (1-473): 6.68e-148: 433: 26.72
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (7-474): 9.71e-142: 418: 27.09
+	Hs
		1204911 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI50_HUMAN (1-487): 5.07e-137: 405: 100.00
+	Hs
		849360 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI50_HUMAN (1-487): 5.07e-137: 405: 100.00
+	Hs
		537142 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI27_HUMAN (1-475): 2.7e-134: 399: 27.11
+	Hs
		536760 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI27_HUMAN (1-475): 2.7e-134: 399: 27.11
+	Hs
		849406 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI11_HUMAN (1-482): 8.18e-131: 389: 26.84
+	Hs
		849358 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI69_HUMAN (1-473): 6.11e-123: 369: 26.63
+	Hs
		849366 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI22_HUMAN (1-475): 1.16e-120: 364: 24.41
+	Hs
		135045 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI38_HUMAN (1-474): 4.59e-120: 361: 24.95
+	Hs
		135012 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI38_HUMAN (1-474): 4.59e-120: 361: 24.95
+	Hs
		1318719 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM5_HUMAN (1-475): 2.45e-116: 353: 25.00
+	Hs
		1377469 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI17_HUMAN (1-463): 4.08e-114: 346: 23.69
+	Hs
		1313765 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI62_HUMAN (9-470): 4.7e-113: 343: 27.97
+	Hs
		1354526 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI10_HUMAN (1-462): 2.58e-111: 339: 25.00
+	Hs
		849347 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI72_HUMAN (1-477): 4.48e-109: 333: 31.06
+	Hs
		1285831 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI43_HUMAN (10-457): 2.23e-107: 328: 19.12
+	Hs
		849399 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI43_HUMAN (10-457): 2.23e-107: 328: 19.12
+	Hs
		1357712 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI35_HUMAN (3-473): 6.13e-102: 316: 25.72
+	Hs
		849384 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI41_HUMAN (1-44): 3.64e-10: 64.1: 31.25