Protein: ETV6
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)

Gene: ETV6
Organism: Homo sapiens
Interactions: 118
UniProt ID: P41212

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833043

ETV7
Transcription factor ETV7

4

19

High-throughput

0.903

High

832956

ETV6
Transcription factor ETV6

4

19

Small-scale

0.873

High

832971

FLI1
Friend leukemia integration 1 transcription factor

1

18

Small-scale

0.740

High

287533

LRP6
Low-density lipoprotein receptor-related protein 6

5

2

High-throughput

0.714

High

832984

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

5

1

High-throughput

0.713

High

832980

TRAF3
TNF receptor-associated factor 3

4

6

Small-scale

0.694

High

274862

LRP5
Low-density lipoprotein receptor-related protein 5

4

1

High-throughput

0.691

High

832986

NID2
Nidogen-2

3

2

High-throughput

0.667

High

278261

NCOR1
Nuclear receptor corepressor 1

2

14

Small-scale

0.631

High

832970

UBC9
SUMO-conjugating enzyme UBC9

2

9

Small-scale

0.631

High

832978

FOXC1
Forkhead box protein C1

1

14

High-throughput

0.618

High

832983

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

12

High-throughput

0.618

High

832992

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.603

High

832981

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

1

High-throughput

0.601

High

193226

SOCS1
Suppressor of cytokine signaling 1

2

3

Small-scale

0.584

High

832968

SUMO1
Small ubiquitin-related modifier 1

2

5

Small-scale

0.584

High

833005

KAT5
Histone acetyltransferase KAT5

1

8

Small-scale

0.573

High

371374

MYC
Myc proto-oncogene protein

2

17

High-throughput

0.571

High

395634

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

832967

GRB2
Growth factor receptor-bound protein 2

1

6

Small-scale

0.561

High

833041

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

10

Small-scale

0.561

High

833010

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.549

High

833021

AP1M1
AP-1 complex subunit mu-1

1

0

High-throughput

0.549

High

832959

SOX2
Transcription factor SOX-2

1

18

High-throughput

0.536

High

833006

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.536

High

833024

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.536

High

833030

KLHL9
Kelch-like protein 9

1

4

High-throughput

0.536

High

833031

KLH13
Kelch-like protein 13

1

4

High-throughput

0.536

High

833033

HDAC6
Protein deacetylase HDAC6

1

11

High-throughput

0.536

High

833036

HDAC9
Histone deacetylase 9

1

11

Small-scale

0.534

High

832961

CEBPA
CCAAT/enhancer-binding protein alpha

1

15

High-throughput

0.527

High

832993

VP26B
Vacuolar protein sorting-associated protein 26B

1

0

High-throughput

0.513

High

833012

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

832999

FBXL6
F-box/LRR-repeat protein 6

1

4

Small-scale

0.512

High

299094

FLOT1
Flotillin-1

1

9

High-throughput

0.500

High

832987

FLOT2
Flotillin-2

1

9

High-throughput

0.500

High

833018

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

13

High-throughput

0.500

High

181066

AXIN1
Axin-1

1

1

High-throughput

0.481

High

832977

TRAF2
TNF receptor-associated factor 2

1

6

High-throughput

0.481

High

131789

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

155920

SOCS3
Suppressor of cytokine signaling 3

1

7

Small-scale

0.479

High

169991

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

174957

SC16A
Protein transport protein Sec16A

1

8

High-throughput

0.479

High

188200

HDAC3
Histone deacetylase 3

1

10

Small-scale

0.479

High

220878

XPOT
Exportin-T

1

1

High-throughput

0.479

High

240972

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

259569

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

297768

PIAS2
E3 SUMO-protein ligase PIAS2

1

12

High-throughput

0.479

High

324100

CE152
Centrosomal protein of 152 kDa

1

1

High-throughput

0.479

High

385521

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.479

High

473838

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

484072

PGFRB
Platelet-derived growth factor receptor beta

1

2

Small-scale

0.479

High

775494

NU214
Nuclear pore complex protein Nup214

1

11

High-throughput

0.479

High

798796

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

832957

NKX21
Homeobox protein Nkx-2.1

1

20

High-throughput

0.479

High

832958

CRKL
Crk-like protein

1

5

Small-scale

0.479

High

832962

NUP98
Nuclear pore complex protein Nup98-Nup96

1

5

High-throughput

0.479

High

832963

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

832964

SEC13
Protein SEC13 homolog

1

14

High-throughput

0.479

High

832965

RBM11
Splicing regulator RBM11

1

3

High-throughput

0.479

High

832966

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.479

High

832972

IRF8
Interferon regulatory factor 8

1

10

Small-scale

0.479

High

832973

TLE3
Transducin-like enhancer protein 3

1

17

High-throughput

0.479

High

832975

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

832976

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

832979

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

High-throughput

0.479

High

832988

MDC1
Mediator of DNA damage checkpoint protein 1

1

15

High-throughput

0.479

High

832989

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

832990

OZF
Zinc finger protein OZF

1

1

High-throughput

0.479

High

832991

TRIP6
Thyroid receptor-interacting protein 6

1

5

High-throughput

0.479

High

832995

CEP85
Centrosomal protein of 85 kDa

1

2

High-throughput

0.479

High

833000

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

1

15

High-throughput

0.479

High

833001

ALMS1
Centrosome-associated protein ALMS1

1

8

High-throughput

0.479

High

833003

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

833004

ESR2
Estrogen receptor beta

1

16

High-throughput

0.479

High

833009

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

833013

SIN3A
Paired amphipathic helix protein Sin3a

1

5

Small-scale

0.479

High

833016

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

1

14

High-throughput

0.479

High

833026

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

17

High-throughput

0.479

High

833028

M1IP1
Mid1-interacting protein 1

1

1

High-throughput

0.479

High

833034

ZMYM2
Zinc finger MYM-type protein 2

1

6

High-throughput

0.479

High

833035

LIMD1
LIM domain-containing protein 1

1

8

High-throughput

0.479

High

833038

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

1

High-throughput

0.479

High

833039

GAB2
GRB2-associated-binding protein 2

1

3

Small-scale

0.479

High

67629

RHG32
Rho GTPase-activating protein 32

1

0

High-throughput

0.458

High

832969

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

832998

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.458

High

833002

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.458

High

833015

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.458

High

833029

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

833037

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.458

High

3340

A0A0S2Z4M1
Axin-1

1

1

High-throughput

0.457

High

832974

LG3BP
Galectin-3-binding protein

1

6

High-throughput

0.457

High

253940

LPXN
Leupaxin

1

4

High-throughput

0.445

High

536659

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.445

High

832960

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

1

1

High-throughput

0.445

High

832982

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

832994

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.445

High

833007

FBXW7
F-box/WD repeat-containing protein 7

1

5

High-throughput

0.445

High

833014

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.445

High

833019

TRI62
E3 ubiquitin-protein ligase TRIM62

1

2

High-throughput

0.445

High

789070

NUP62
Nuclear pore glycoprotein p62

1

8

High-throughput

0.437

High

832996

NUP54
Nucleoporin p54

1

2

High-throughput

0.437

High

833020

DDA1
DET1- and DDB1-associated protein 1

1

2

High-throughput

0.437

High

833025

GRPE1
GrpE protein homolog 1, mitochondrial

1

5

High-throughput

0.437

High

832985

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

833011

HIPL1
HHIP-like protein 1

1

1

High-throughput

0.407

High

833017

WDR83
WD repeat domain-containing protein 83

1

13

High-throughput

0.407

High

833032

WRP73
WD repeat-containing protein WRAP73

1

4

High-throughput

0.407

High

261475

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

833008

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

833022

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

833023

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low

833027

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

833042

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.249

Low

832997

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

0

High-throughput

0.232

Low

833040

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025