HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: RNF38 (Q9H0F5)
E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38)
Gene: RNF38

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.710

Property	Details
Experiments	31638574
Identification Methods	x-ray crystallography, pull down
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 515
+	Hs
		1327690 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RNF38_HUMAN (1-515): 5.32e-114: 348: 100.00
+	Hs
		849443 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RNF38_HUMAN (1-515): 5.32e-114: 348: 100.00
+	Hs
		1169203 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN111_HUMAN (2-508): 6.5e-50: 186: 17.74
+	Hs
		196372 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		PJA2_HUMAN (59-514): 6.53e-51: 186: 14.62
+	Hs
		196282 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		PJA2_HUMAN (59-514): 6.53e-51: 186: 14.62
+	Hs
		849348 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RN111_HUMAN (2-508): 6.5e-50: 186: 17.74
+	Hs
		1313520 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN126_HUMAN (253-514): 1e-42: 156: 19.29
+	Hs
		849428 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RN126_HUMAN (253-514): 1e-42: 156: 19.29
+	Hs
		1377467 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN115_HUMAN (260-515): 7.52e-39: 145: 17.36
+	Hs
		1346940 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RNF12_HUMAN (13-508): 1.16e-32: 133: 16.41
+	Hs
		1170316 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		ARK2C_HUMAN (158-510): 4e-31: 125: 19.95
+	Hs
		849350 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		ARK2C_HUMAN (158-510): 4e-31: 125: 19.95
+	Zm
		74334 B4FC97_MAIZE (4-149): 4.83e-81: 237: 46.58		B6U926_MAIZE (267-515): 7.12e-30: 122: 16.36
+	Hs
		1242076 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		ZNRF1_HUMAN (290-501): 1.92e-31: 122: 15.25
+	Zm
		79637 B6SZE0_MAIZE (4-149): 7.83e-81: 236: 47.95		B6U926_MAIZE (267-515): 7.12e-30: 122: 16.36
+	Hs
		849373 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		ZNRF1_HUMAN (290-501): 1.92e-31: 122: 15.25
+	At
		715128 UBC8_ARATH (4-149): 2.42e-80: 235: 46.58		CIP8_ARATH (264-515): 6.52e-30: 121: 14.89
+	Hs
		1356934 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN150_HUMAN (429-510): 8.55e-27: 114: 32.93
+	Hs
		207572 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RNF13_HUMAN (440-509): 6.48e-27: 114: 36.62
+	Hs
		207545 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RNF13_HUMAN (440-509): 6.48e-27: 114: 36.62