Protein: HOME1
Homer protein homolog 1 (Homer-1)

Gene: HOME1, HOMER1
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q86YM7

Gene Ontology (top 5):
GO:0003009 - skeletal muscle contraction
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007206 - phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1295218

HOME3
Homer protein homolog 3

7

15

High-throughput

0.973

High

1295217

HOME2
Homer protein homolog 2

5

16

High-throughput

0.927

High

1295209

SARG
Specifically androgen-regulated gene protein

6

1

High-throughput

0.737

High

136706

TRAF5
TNF receptor-associated factor 5

5

19

High-throughput

0.717

High

1160679

DREB
Drebrin

4

9

High-throughput

0.697

High

1295224

ABI3
ABI gene family member 3

4

20

High-throughput

0.692

High

242187

PRKN
E3 ubiquitin-protein ligase parkin

4

14

Small-scale

0.682

High

1271977

CENPQ
Centromere protein Q

3

1

High-throughput

0.668

High

482924

TPM1
Tropomyosin alpha-1 chain

3

9

High-throughput

0.667

High

1051793

EF1A2
Elongation factor 1-alpha 2

3

1

High-throughput

0.667

High

1115549

ASPP2
Apoptosis-stimulating of p53 protein 2

3

11

High-throughput

0.667

High

1295210

SPTN4
Spectrin beta chain, non-erythrocytic 4

3

20

High-throughput

0.667

High

1295188

HOME1
Homer protein homolog 1

1

16

Small-scale

0.647

High

1276129

NUP54
Nucleoporin p54

4

2

High-throughput

0.638

High

1295220

IFT57
Intraflagellar transport protein 57 homolog

4

2

High-throughput

0.630

High

641341

RYR1
Ryanodine receptor 1

2

8

Small-scale

0.629

High

1200991

ACTBL
Beta-actin-like protein 2

2

14

High-throughput

0.628

High

1295194

KIF2B
Kinesin-like protein KIF2B

2

2

High-throughput

0.628

High

1295222

CEP72
Centrosomal protein of 72 kDa

2

4

High-throughput

0.628

High

321925

FRYL
Protein furry homolog-like

3

1

High-throughput

0.616

High

1169010

CSPP1
Centrosome and spindle pole-associated protein 1

2

1

High-throughput

0.611

High

1295206

GRM2B
GRAM domain-containing protein 2B

3

1

High-throughput

0.609

High

1295219

FBX28
F-box only protein 28

3

1

High-throughput

0.609

High

319224

FCSD2
F-BAR and double SH3 domains protein 2

2

16

High-throughput

0.606

High

1089324

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

2

2

High-throughput

0.606

High

1295189

RASL3
RAS protein activator like-3

2

11

High-throughput

0.606

High

1295191

ABI1
Abl interactor 1

2

20

High-throughput

0.606

High

1295230

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

2

20

High-throughput

0.606

High

1207955

COL12
Collectin-12

2

0

High-throughput

0.602

High

1295221

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.602

High

1227002

A16L1
Autophagy-related protein 16-1

2

20

High-throughput

0.601

High

1295197

INADL
InaD-like protein

2

14

High-throughput

0.576

High

1295216

MED4
Mediator of RNA polymerase II transcription subunit 4

2

2

High-throughput

0.574

High

1295233

EMIL1
EMILIN-1

2

6

High-throughput

0.574

High

1295207

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

8

Small-scale

0.561

High

297834

PIAS2
E3 SUMO-protein ligase PIAS2

2

2

High-throughput

0.553

High

1295232

ARIP4
Helicase ARIP4

2

2

High-throughput

0.553

High

447802

TPM3
Tropomyosin alpha-3 chain

1

6

High-throughput

0.536

High

718423

CD6
T-cell differentiation antigen CD6

1

3

High-throughput

0.536

High

730026

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

749958

KINH
Kinesin-1 heavy chain

1

2

High-throughput

0.536

High

990452

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1127966

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

1

High-throughput

0.536

High

1179808

INSY1
Inhibitory synaptic factor 1

1

3

High-throughput

0.536

High

1186406

ASTRB
Protein Aster-B

1

1

High-throughput

0.536

High

1234756

SPOPL
Speckle-type POZ protein-like

1

5

High-throughput

0.536

High

1287166

MYPN
Myopalladin

1

10

High-throughput

0.536

High

1295199

BRK1
Protein BRICK1

1

1

High-throughput

0.536

High

1295200

PALLD
Palladin

1

11

High-throughput

0.536

High

1295215

RABE2
Rab GTPase-binding effector protein 2

1

15

High-throughput

0.536

High

1295223

STK26
Serine/threonine-protein kinase 26

1

17

High-throughput

0.536

High

1295227

TNIK
TRAF2 and NCK-interacting protein kinase

1

17

High-throughput

0.536

High

1155002

ADIPO
Adiponectin

1

0

High-throughput

0.513

High

1295190

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.513

High

1295212

BORG4
Cdc42 effector protein 4

1

0

High-throughput

0.513

High

1127575

FAT1
Protocadherin Fat 1

1

5

Small-scale

0.501

High

1295202

RYR2
Ryanodine receptor 2

1

10

Small-scale

0.501

High

1295226

DBNL
Drebrin-like protein

1

20

Small-scale

0.501

High

133035

MATN2
Matrilin-2

1

1

High-throughput

0.489

High

574024

HXB2
Homeobox protein Hox-B2

1

6

High-throughput

0.489

High

1257270

STXB4
Syntaxin-binding protein 4

1

20

High-throughput

0.489

High

1295204

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.489

High

157576

CTRO
Citron Rho-interacting kinase

1

13

High-throughput

0.479

High

244171

KIF5C
Kinesin heavy chain isoform 5C

1

2

High-throughput

0.479

High

293962

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.479

High

375685

RASK
GTPase KRas

1

20

High-throughput

0.479

High

835443

GRM5
Metabotropic glutamate receptor 5

1

10

Small-scale

0.479

High

862273

YAP1
Transcriptional coactivator YAP1

1

20

Small-scale

0.479

High

878232

TRPC1
Short transient receptor potential channel 1

1

6

Small-scale

0.479

High

952938

ACTB
Actin, cytoplasmic 1

1

14

High-throughput

0.479

High

970734

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.479

High

1099655

GRM1
Metabotropic glutamate receptor 1

1

10

Small-scale

0.479

High

1295195

NHLC2
NHL repeat-containing protein 2

1

3

High-throughput

0.479

High

1295201

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1295203

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

2

High-throughput

0.479

High

1295211

TXNIP
Thioredoxin-interacting protein

1

1

Small-scale

0.479

High

1295214

RNF41
E3 ubiquitin-protein ligase NRDP1

1

16

Small-scale

0.479

High

1295229

TRPC5
Short transient receptor potential channel 5

1

6

Small-scale

0.479

High

1295231

NCKP1
Nck-associated protein 1

1

5

High-throughput

0.479

High

63730

A5PKX9
INADL protein

1

19

High-throughput

0.470

High

977034

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.458

High

1295196

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

239116

ZNRD2
Protein ZNRD2

1

3

High-throughput

0.445

High

391330

FRIL
Ferritin light chain

1

3

High-throughput

0.445

High

404834

PRIO
Major prion protein

1

1

High-throughput

0.445

High

530041

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

1295193

PALS1
Protein PALS1

1

6

High-throughput

0.445

High

1295205

DYL2
Dynein light chain 2, cytoplasmic

1

7

High-throughput

0.445

High

106218

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

1258491

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

6

High-throughput

0.407

High

1295228

PNMA2
Paraneoplastic antigen Ma2

1

4

High-throughput

0.407

High

50916

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.328

High

1295198

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.328

High

1244758

SYCE2
Synaptonemal complex central element protein 2

2

0

High-throughput

0.316

High

1295192

FAM9A
Protein FAM9A

2

0

High-throughput

0.316

High

1295225

ZMYM5
Zinc finger MYM-type protein 5

2

0

High-throughput

0.316

High

1081589

BRME1
Break repair meiotic recombinase recruitment factor 1

1

0

High-throughput

0.299

High

1295213

KDM4C
Lysine-specific demethylase 4C

1

0

High-throughput

0.279

Low

1295208

Q9BPY1
C1orf116 protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025