HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: BFAR (Q9NZS9)
Bifunctional apoptosis regulator (RING finger protein 47)
Gene: BFAR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 450
+	Hs
		1349425 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		BFAR_HUMAN (1-450): 0: 715: 100.00
+	Hs
		1204911 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI50_HUMAN (23-183): 1.32e-43: 161: 19.63
+	Hs
		1318719 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM5_HUMAN (22-194): 1.52e-39: 150: 20.11
+	Hs
		1318532 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI31_HUMAN (27-181): 2.52e-32: 128: 17.61
+	Hs
		584907 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RO52_HUMAN (19-185): 1.37e-31: 127: 17.24
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (7-145): 1.43e-30: 125: 17.61
+	Hs
		1377469 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI17_HUMAN (26-140): 1.23e-30: 125: 21.26
+	Hs
		1357712 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI35_HUMAN (15-145): 3.59e-30: 123: 21.90
+	Hs
		849314 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI26_HUMAN (19-141): 3.03e-30: 124: 18.66
+	Hs
		537142 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI27_HUMAN (26-141): 1.52e-29: 122: 19.84
+	Hs
		536760 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI27_HUMAN (26-141): 1.52e-29: 122: 19.84
+	Hs
		135045 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI38_HUMAN (19-182): 2.06e-28: 118: 17.24
+	Hs
		135012 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI38_HUMAN (19-182): 2.06e-28: 118: 17.24
+	Hs
		1354526 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI10_HUMAN (19-145): 5.11e-28: 117: 18.52
+	Hs
		1285831 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI43_HUMAN (21-139): 8.3e-27: 113: 26.23
+	Hs
		282581 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RNF8_HUMAN (3-103): 3.2e-23: 103: 28.85
+	Hs
		1052807 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI25_HUMAN (30-102): 2.81e-20: 95.4: 28.95
+	Hs
		849330 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI25_HUMAN (30-102): 2.81e-20: 95.4: 28.95
+	Hs
		1318358 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM8_HUMAN (30-93): 1.76e-10: 65: 32.84
+	Hs
		1290204 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN125_HUMAN (4-74): 8.22e-10: 60.8: 32.39