Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: CSN1 (Q13098)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Gene: GPS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32296183, 32034103, 33961781, 16045761, 31444342, 22414063, 19141280, 10903862, 11114242, 25043011, 19444310, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, far western blotting, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 443
Hs

1 491
+ Mm
+ Hs
+ At
+ An
+ Hs
+ Hs
+ Ce
+ Hs
+ An
+ Hs
+ Dm
+ Dm
+ Dm
+ Ce
+ Sp
+ Zm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024