HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 183
+	Hs
		884294 CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00		UBE2A_HUMAN (4-150): 3.11e-64: 196: 30.46
+	Hs
		667644 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		UBE2A_HUMAN (4-150): 3.11e-64: 196: 30.46
+	Hs
		667719 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00
+	Hs
		971199 CDK12_HUMAN (16-371): 2.05e-123: 390: 42.54		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00
+	Hs
		703527 MK01_HUMAN (5-359): 5.51e-133: 386: 30.99		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00
+	Hs
		443291 CDK1_HUMAN (16-315): 1.05e-123: 359: 40.40		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00
+	Hs
		884317 CDK5_HUMAN (16-317): 5.5e-118: 345: 39.93		UBE2A_HUMAN (4-150): 3.11e-64: 196: 30.46
+	Hs
		970343 CDK5_HUMAN (16-317): 5.5e-118: 345: 39.93		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00