HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: OSB10 (Q9BXB5)
Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10)
Gene: OSBPL10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 764
+	Hs
		925582 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		OSB10_HUMAN (1-764): 0: 752: 100.00
+	Hs
		951289 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		OSB10_HUMAN (1-764): 0: 752: 100.00
+	Hs
		894383 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		OSB10_HUMAN (1-764): 0: 752: 100.00
+	Hs
		545593 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		OSB10_HUMAN (1-764): 0: 752: 100.00
+	Hs
		900858 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		OSB11_HUMAN (20-762): 0: 682: 53.94
+	Hs
		925581 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		OSB11_HUMAN (20-762): 0: 682: 53.94
+	Hs
		951288 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		OSB11_HUMAN (20-762): 0: 682: 53.94
+	Hs
		545592 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		OSB11_HUMAN (20-762): 0: 682: 53.94
+	Hs
		545575 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		OSBL9_HUMAN (74-762): 0: 625: 34.51
+	Hs
		900866 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20
+	Hs
		925589 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20
+	Hs
		436490 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20
+	Hs
		951303 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20
+	Hs
		894394 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20
+	Hs
		545597 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20
+	Sc
		419682 RHO1_YEAST (3-188): 1.51e-97: 283: 73.12		KES1_YEAST (396-748): 2.84e-94: 302: 23.64
+	Hs
		900901 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		OSBL3_HUMAN (53-363): 8.62e-18: 90.3: 15.43
+	Hs
		925615 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		OSBL3_HUMAN (53-363): 8.62e-18: 90.3: 15.43
+	Hs
		436507 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		OSBL3_HUMAN (53-363): 8.62e-18: 90.3: 15.43
+	Hs
		951338 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		OSBL3_HUMAN (53-363): 8.62e-18: 90.3: 15.43