Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C
Interactor 2: DP13B (Q8NEU8)
DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)
Gene: APPL2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.926 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 34079125, 31515488, unassigned1304 |
| Identification Methods | two hybrid, proximity labelling technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~Ras |
| Common GO terms | GO:0005768 - endosome GO:0005886 - plasma membrane GO:0031901 - early endosome membrane GO:0070062 - extracellular exosome |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025