HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0043197 - dendritic spine
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1098
+	Hs
		925725 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		436569 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		951455 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		900762 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		951207 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		900424 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		925239 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		436278 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		950954 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		900482 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SLMAP_HUMAN (659-1098): 1.13e-59: 222: 18.59
+	Mm
		925797 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Mm
		1164086 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		925799 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		892727 CDC42_MOUSE (1-193): 5.51e-77: 230: 52.33		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		876341 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		900421 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		925236 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		436277 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		893945 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		900710 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		INADL_HUMAN (300-819): 1.83e-15: 84: 10.38