Protein: ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)

Gene: ACAP2
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q15057

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0005096 - GTPase activator activity
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
GO:0010008 - endosome membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1140287

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

3

15

High-throughput

0.855

High

249753

DOK2
Docking protein 2

2

5

High-throughput

0.737

High

631230

RAB5A
Ras-related protein Rab-5A

2

10

High-throughput

0.737

High

635719

RASA1
Ras GTPase-activating protein 1

2

20

High-throughput

0.737

High

702349

ELK4
ETS domain-containing protein Elk-4

2

2

High-throughput

0.659

High

273135

RFIP3
Rab11 family-interacting protein 3

1

12

Small-scale

0.618

High

975042

ARF6
ADP-ribosylation factor 6

1

12

High-throughput

0.618

High

1140280

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.618

High

1140283

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.618

High

1140285

SNX27
Sorting nexin-27

1

14

High-throughput

0.618

High

1140291

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

4

High-throughput

0.618

High

867146

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.586

High

955932

RAB8A
Ras-related protein Rab-8A

1

4

Small-scale

0.575

High

529823

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.536

High

1140295

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.517

High

1140292

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

415585

HSPB1
Heat shock protein beta-1

1

9

High-throughput

0.494

High

136897

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.479

High

241725

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

724478

GDIA
Rab GDP dissociation inhibitor alpha

1

1

High-throughput

0.479

High

951681

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.479

High

971545

1433E
14-3-3 protein epsilon

1

8

Small-scale

0.479

High

1140284

EHBP1
EH domain-binding protein 1

1

7

High-throughput

0.479

High

1140293

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1140294

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

212571

GPAA1
GPI-anchor transamidase component GPAA1

1

0

High-throughput

0.458

High

319776

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

773880

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.458

High

1140281

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1140286

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

0

High-throughput

0.458

High

1140289

PIGS
GPI-anchor transamidase component PIGS

1

0

High-throughput

0.458

High

293710

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

768240

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

970530

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1126893

RBM39
RNA-binding protein 39

1

2

High-throughput

0.437

High

1135681

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.437

High

1140288

CIC
Protein capicua homolog

1

10

High-throughput

0.437

High

1140290

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

1140279

PDK3
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

192492

INSI1
Insulin-induced gene 1 protein

1

0

High-throughput

0.249

Low

464265

FUMH
Fumarate hydratase, mitochondrial

1

0

High-throughput

0.249

Low

702588

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.249

Low

957386

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.249

Low

1140282

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025