HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: DAPLE (Q9P219)
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
Gene: CCDC88C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030054 - cell junction GO:0031122 - cytoplasmic microtubule organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 2028
+	Hs
		900534 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		925322 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		436338 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		951040 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		894079 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		545414 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		892403 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Mm
		916115 RHOB_MOUSE (1-191): 1.62e-73: 221: 83.94		MAP1A_MOUSE (1287-2020): 9.65e-76: 283: 14.47
+	Mm
		823539 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		CTRO_MOUSE (140-948): 1.4e-46: 187: 17.23
+	Mm
		823530 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CTRO_MOUSE (140-948): 1.4e-46: 187: 17.23
+	Mm
		823529 CDC42_MOUSE (1-193): 5.51e-77: 230: 52.33		CTRO_MOUSE (140-948): 1.4e-46: 187: 17.23
+	Hs
		725138 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		725125 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		148608 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		148653 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		148297 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		724757 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		148632 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		724776 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		894047 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ITSN1_HUMAN (60-424): 6.95e-14: 79.9: 11.52