HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 2365
+	Hs
		915963 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		925603 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		915771 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		901188 RND3_HUMAN (1-244): 1.15e-81: 246: 100.00		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		522630 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		MYH7_HUMAN (1667-2364): 7.9e-42: 172: 10.69
+	Hs
		894572 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		MUC12_HUMAN (3-1364): 6.12e-46: 186: 11.77
+	Hs
		254433 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		254467 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		254468 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Ce
		136800 RHO1_CAEEL (22-200): 2.46e-93: 274: 50.28		UNC89_CAEEL (392-957): 7.22e-20: 100: 14.04
+	Hs
		725125 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		724757 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		551793 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		297809 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18
+	Hs
		297822 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18
+	Ce
		136793 RAC1_CAEEL (24-208): 1.83e-77: 233: 43.78		UNC89_CAEEL (392-957): 7.22e-20: 100: 14.04
+	Hs
		551652 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		551653 RND3_HUMAN (1-244): 1.15e-81: 246: 100.00		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		297823 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18
+	Hs
		925204 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82