HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 1382
+	Hs
		903240 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		903334 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		MYH14_HUMAN (488-1381): 1.41e-12: 75.1: 9.26
+	Hs
		551655 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		903399 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18
+	Hs
		551632 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		1302927 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		MINT_HUMAN (485-1376): 2.77e-41: 169: 13.43
+	Hs
		724952 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		1288351 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		ITSN2_HUMAN (542-870): 1.01e-49: 196: 21.46
+	Hs
		551766 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		725215 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Hs
		1288258 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		MINT_HUMAN (485-1376): 2.77e-41: 169: 13.43
+	Hs
		551723 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		1068625 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		551854 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		1281519 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		MRCKB_HUMAN (610-1132): 1.14e-14: 82: 10.96
+	Hs
		1189782 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		MYH14_HUMAN (488-1381): 1.41e-12: 75.1: 9.26
+	Hs
		728492 POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73		MYH11_HUMAN (79-823): 1.69e-23: 110: 11.10
+	Hs
		1268063 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18
+	Hs
		197084 PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39		CP250_HUMAN (74-918): 1.12e-17: 92: 10.23
+	Hs
		61736 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		A6H8W8_HUMAN (593-996): 3.46e-14: 80.1: 14.29