HitPredict

Interactor 1: SMCA2 (P51531)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SAMRCA2) (EC 3.6.4.-) (BRG1-associated factor 190B) (BAF190B) (Probable global transcription activator SNF2L2) (Protein brahma homolog) (hBRM) (SNF2-alpha)
Gene: SMARCA2

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SnAC, Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1590 Hs			1 127
+	Hs
		903118 SMCA2_HUMAN (1-1590): 0: 1105: 100.00		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		903383 SMCA4_HUMAN (1-1588): 0: 991: 71.12		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		903304 SMCA4_HUMAN (1-1588): 0: 991: 71.12		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		703328 SMCA1_HUMAN (617-1558): 0: 830: 28.26		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		703288 SMCA1_HUMAN (617-1558): 0: 830: 28.26		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		243652 SMCA5_HUMAN (584-1564): 0: 826: 26.28		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		243554 SMCA5_HUMAN (584-1564): 0: 826: 26.28		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		243588 SMCA5_HUMAN (584-1564): 0: 826: 26.28		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		243698 SMCA5_HUMAN (584-1564): 0: 826: 26.28		H2B1H_HUMAN (5-127): 5.54e-54: 166: 85.37
+	Hs
		1132729 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		1132877 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1H_HUMAN (5-127): 5.54e-54: 166: 85.37
+	Hs
		256858 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25
+	Hs
		754848 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		946779 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1D_HUMAN (1-127): 1.38e-53: 166: 85.04
+	Hs
		980773 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		1132882 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1A_HUMAN (1-127): 1.73e-52: 163: 100.00
+	Hs
		1132929 CHD4_HUMAN (386-1589): 0: 766: 22.34		H2B1L_HUMAN (1-127): 1.36e-52: 163: 85.83
+	Hs
		256932 CHD5_HUMAN (430-1582): 0: 760: 21.73		H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25
+	Sc
		381663 ISW2_YEAST (539-1580): 0: 782: 24.36		H2B2_YEAST (4-126): 4.48e-41: 134: 69.36
+	Sc
		381496 ISW1_YEAST (516-1588): 0: 763: 24.67		H2B2_YEAST (4-126): 4.48e-41: 134: 69.36