HitPredict

Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: WDR74 (Q6RFH5)
WD repeat-containing protein 74 (NOP seven-associated protein 1)
Gene: WDR74

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 385
+	Hs
		905114 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		TBL1R_HUMAN (82-377): 1.53e-64: 215: 13.59
+	Hs
		261386 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		TBL1X_HUMAN (82-377): 1.93e-63: 214: 12.62
+	Mm
		1296653 MECP2_MOUSE (1-486): 5.36e-112: 341: 94.44		TBL1R_MOUSE (82-377): 1.69e-64: 215: 13.59
+	Hs
		905194 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		NLE1_HUMAN (128-383): 1.24e-51: 181: 15.02
+	Hs
		905015 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		SNR40_HUMAN (2-253): 7.03e-50: 173: 12.06
+	Hs
		284933 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		TAF5L_HUMAN (100-321): 9.66e-18: 86.8: 16.40
+	Hs
		352273 MBD3_HUMAN (93-249): 3.07e-43: 156: 26.88		FBW1A_HUMAN (24-374): 1.55e-71: 236: 14.72
+	Hs
		1361892 TITIN_HUMAN (240-472): 1.29e-12: 72.8: 19.57		SNR40_HUMAN (2-253): 7.03e-50: 173: 12.06
+	Hs
		1380238 MBD1_HUMAN (95-220): 7.01e-31: 127: 31.78		FBXW7_HUMAN (3-154): 1.36e-20: 95.6: 15.39