HitPredict

Interactor 1: TSN5 (P62079)
Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9)
Gene: TSPAN5

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26686862
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 268 Hs			1 613
+	Hs
		326168 TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		653096 CD82_HUMAN (11-267): 6.94e-60: 192: 28.09		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		887922 CD81_HUMAN (12-264): 9.13e-50: 165: 22.99		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		602274 CD9_HUMAN (11-265): 6.79e-48: 160: 24.32		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Mm
		728559 CD81_MOUSE (12-264): 1e-48: 162: 22.61		IGSF8_MOUSE (22-613): 1.44e-171: 503: 90.20
+	Hs
		905572 TSN5_HUMAN (1-268): 1.69e-88: 265: 100.00		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		1245273 TSN14_HUMAN (1-266): 3.18e-84: 254: 58.27		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		326244 TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		653105 CD82_HUMAN (11-267): 6.94e-60: 192: 28.09		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		819474 CD151_HUMAN (5-266): 2.12e-56: 182: 22.64		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		446077 CD63_HUMAN (11-263): 1.04e-55: 180: 24.90		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		253639 TSN5_HUMAN (1-268): 1.69e-88: 265: 100.00		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		887973 CD81_HUMAN (12-264): 9.13e-50: 165: 22.99		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		253665 TSN14_HUMAN (1-266): 3.18e-84: 254: 58.27		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		602290 CD9_HUMAN (11-265): 6.79e-48: 160: 24.32		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		1199563 TSN33_HUMAN (7-264): 7.73e-76: 233: 42.64		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		888000 CD81_HUMAN (12-264): 9.13e-50: 165: 22.99		ROBO1_HUMAN (25-507): 1.65e-32: 136: 12.83
+	Hs
		602297 CD9_HUMAN (11-265): 6.79e-48: 160: 24.32		ROBO1_HUMAN (25-507): 1.65e-32: 136: 12.83
+	Hs
		253614 TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		253625 CD9_HUMAN (11-265): 6.79e-48: 160: 24.32		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89