HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1139
+	Hs
		909664 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Mm
		99940 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		SYGP1_MOUSE (2-1138): 0: 768: 43.44
+	Hs
		909931 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		909774 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RASL3_HUMAN (9-789): 1.3e-163: 513: 34.82
+	Hs
		598455 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Mm
		910233 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NF1_MOUSE (293-621): 1.28e-88: 317: 26.45