HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: BRSK1 (Q5RJI5)
Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B)
Gene: BRSK1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Mm			1 778
+	Mm
		910272 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		BRSK2_MOUSE (15-775): 1.65e-168: 505: 70.24
+	Hs
		909786 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		BRSK2_HUMAN (26-775): 3.1e-167: 502: 71.26
+	Mm
		910231 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK3_MOUSE (11-718): 2.4e-162: 490: 25.87
+	Hs
		647862 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK3_HUMAN (11-718): 1.91e-161: 488: 25.47
+	Xl
		223344 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q804T2_XENLA (7-718): 2.28e-161: 487: 25.89
+	Hs
		909730 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK2_HUMAN (7-718): 3.34e-158: 480: 26.27
+	Mm
		910234 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK2_MOUSE (7-718): 2.01e-158: 480: 26.54
+	Xl
		223345 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q8QGV3_XENLA (3-718): 1.35e-154: 471: 27.29
+	Mm
		910308 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK4_MOUSE (9-713): 9.39e-148: 452: 25.83
+	Mm
		910318 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK1_MOUSE (4-718): 4.43e-147: 452: 25.89
+	Hs
		909916 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK4_HUMAN (9-713): 2.21e-147: 451: 26.24
+	Hs
		910106 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK1_HUMAN (5-718): 6.97e-146: 449: 26.30
+	Dm
		90534 1433E_DROME (1-254): 2.95e-146: 411: 82.69		E1JGN0_DROME (5-717): 2.45e-149: 467: 26.75
+	Hs
		910013 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK2_HUMAN (21-763): 3.27e-144: 448: 25.83
+	Hs
		883214 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK1_HUMAN (11-664): 2.49e-145: 447: 30.60
+	Hs
		681770 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AKT1_HUMAN (3-356): 3.58e-143: 431: 27.07
+	Hs
		909507 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AAPK1_HUMAN (31-421): 1.18e-134: 412: 37.15
+	Rn
		871214 1433E_RAT (1-255): 4.87e-154: 430: 100.00		AAPK1_RAT (31-285): 4.09e-80: 269: 50.78
+	Hs
		871354 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AAPK2_HUMAN (31-285): 8.72e-80: 268: 50.39
+	Hs
		910187 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK3_HUMAN (18-370): 3.65e-75: 268: 43.06