HitPredict

Interactor 1: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 28514442, 33961781, 29395067, 15231747, 14667819
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~LSM
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 92
Hs

1 95
+ Hs
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+ Dm
+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024