Interactor 1: SMD1 (P62314)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)
Gene: SNRPD1

Interactor 2: SMD2 (P62316)
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SNRPD2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.923

The method score is based on:

Property Details
Experiments 9417867, 35271311, 30021884, 10025403, 37071682
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, x-ray crystallography, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~LSM
Common GO terms GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 21 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 119
Hs

1 118
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Dm
+ Sc
+ Sc
+ Sp
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024