HitPredict

Interactor 1: SMD1 (P62314)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)
Gene: SNRPD1

Interactor 2: PRP4K (Q13523)
Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)
Gene: PRP4K

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 119 Hs			1 1007
+	Hs
		1037927 LSM4_HUMAN (1-89): 1.24e-33: 115: 23.33		PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00
+	Hs
		911828 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00
+	Dm
		218364 SMD3_DROME (2-102): 6.25e-32: 111: 24.75		DYRK2_DROME (612-1004): 1.73e-112: 365: 30.46
+	Hs
		625313 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45