HitPredict

Interactor 1: SMD1 (P62314)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)
Gene: SNRPD1

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29298432
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0071011 - precatalytic spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 119 Hs			1 953
+	Hs
		1201806 LSM4_HUMAN (1-89): 1.24e-33: 115: 23.33		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1201786 LSM2_HUMAN (1-88): 7.62e-33: 111: 31.11		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		912671 SMD3_HUMAN (2-102): 1.06e-31: 110: 28.71		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		911884 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		912400 SMD1_HUMAN (1-96): 1.18e-34: 117: 100.00		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		912756 SMD3_HUMAN (2-102): 1.06e-31: 110: 28.71		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		912675 SMD3_HUMAN (2-102): 1.06e-31: 110: 28.71		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		911999 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		911892 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14