HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: H2B2C (Q6DN03)
Putative histone H2B type 2-C (H2B-clustered histone 20 pseudogene) (Histone H2B.t) (H2B/t)
Gene: H2BC20P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30021884
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Hs			1 193
+	Hs
		420818 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1J_HUMAN (1-94): 1.78e-40: 135: 93.62
+	Hs
		241492 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1K_HUMAN (1-94): 3.07e-40: 134: 92.55
+	Xl
		355249 H4_XENLA (1-103): 1.38e-48: 151: 100.00		H2B11_XENLA (1-94): 4.03e-40: 134: 87.23
+	Hs
		617943 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1O_HUMAN (1-94): 4.25e-40: 134: 92.55
+	Hs
		917062 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1C_HUMAN (1-94): 4.74e-40: 134: 92.55
+	Hs
		917355 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B2E_HUMAN (1-94): 2.94e-40: 134: 93.62
+	Hs
		917397 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B2F_HUMAN (1-94): 7.09e-40: 134: 90.43
+	Hs
		917700 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1H_HUMAN (1-94): 6.79e-40: 134: 91.49
+	Hs
		707573 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1B_HUMAN (1-94): 1.18e-39: 133: 91.49
+	Hs
		917818 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1M_HUMAN (1-94): 1.42e-39: 133: 88.30
+	Hs
		917819 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1L_HUMAN (1-94): 1.1e-39: 133: 90.43
+	Hs
		886073 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1D_HUMAN (1-94): 1.66e-39: 132: 91.49
+	Hs
		917816 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1N_HUMAN (1-94): 1.53e-39: 132: 91.49
+	Hs
		883007 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2BFS_HUMAN (1-94): 9.65e-39: 131: 90.43
+	Hs
		917708 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2B1A_HUMAN (1-94): 6.61e-36: 123: 75.79
+	Hs
		241620 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		H2B1K_HUMAN (1-94): 3.07e-40: 134: 92.55
+	Hs
		886179 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		H2B1D_HUMAN (1-94): 1.66e-39: 132: 91.49
+	Dm
		355260 H4_DROME (1-103): 4.51e-48: 150: 99.03		H2B_DROME (36-93): 1.6e-29: 107: 86.21
+	Sc
		355713 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H2B2_YEAST (3-94): 2.07e-31: 112: 60.87
+	Sc
		355280 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H2B1_YEAST (3-94): 5.55e-31: 111: 60.87