HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

Property	Details
Experiments	23431171, 26625199, 11742995, 17925393
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 2004
+	At
		886859 H4_ARATH (1-103): 3.47e-48: 150: 98.06		MYST2_ARATH (351-783): 3e-162: 506: 39.50
+	Dm
		950399 H4_DROME (1-103): 4.51e-48: 150: 99.03		TIP60_DROME (292-779): 7.28e-155: 490: 32.81
+	Hs
		309685 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Sc
		356770 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ESA1_YEAST (378-787): 2.7e-150: 474: 36.36
+	Hs
		917932 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT8_HUMAN (357-789): 2.81e-138: 441: 37.73
+	Hs
		917696 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Hs
		1304373 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		KAT8_HUMAN (357-789): 2.81e-138: 441: 37.73
+	Sc
		356383 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SAS3_YEAST (486-860): 1.72e-122: 410: 32.69
+	Dm
		137452 H4_DROME (1-103): 4.51e-48: 150: 99.03		MOF_DROME (401-782): 6.63e-111: 376: 36.98
+	Sc
		356532 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SAS2_YEAST (507-761): 6.32e-94: 310: 30.77
+	Hs
		917182 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		917683 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Sc
		356778 H4_YEAST (18-103): 6.13e-41: 132: 90.70		MDN1_YEAST (1014-1648): 5.68e-46: 186: 15.52
+	Hs
		917267 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MDC1_HUMAN (807-1825): 3.66e-30: 133: 11.19
+	Hs
		152623 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KMT2D_HUMAN (193-311): 2.94e-25: 117: 33.61
+	Hs
		917621 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KMT2C_HUMAN (229-311): 4.1e-22: 107: 37.35
+	Hs
		917128 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ANK2_HUMAN (749-1909): 1.85e-16: 88.5: 10.39
+	Hs
		917792 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MINT_HUMAN (748-1864): 3.86e-13: 77.8: 10.17