HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: TRI36 (Q9NQ86)
E3 ubiquitin-protein ligase TRIM36 (EC 2.3.2.27) (RING finger protein 98) (RING-type E3 ubiquitin transferase TRIM36) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)
Gene: TRIM36

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19232519
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 728
+	Hs
		175730 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI18_HUMAN (24-728): 5.52e-124: 386: 23.45
+	Hs
		175664 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI18_HUMAN (24-728): 5.52e-124: 386: 23.45
+	Hs
		1151762 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		Q6GX22_HUMAN (24-727): 6e-117: 369: 21.73
+	Hs
		1356055 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM1_HUMAN (18-727): 5.37e-113: 360: 20.72
+	Hs
		1052807 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI25_HUMAN (22-723): 2.29e-89: 294: 15.09
+	Hs
		262201 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM3_HUMAN (136-692): 5.7e-67: 236: 12.07
+	Hs
		262167 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRIM3_HUMAN (136-692): 5.7e-67: 236: 12.07
+	Hs
		1318358 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM8_HUMAN (28-421): 5.8e-67: 232: 21.64
+	Hs
		1318738 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM2_HUMAN (119-692): 2.56e-64: 229: 12.00
+	Hs
		1333889 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI45_HUMAN (30-558): 2.25e-64: 226: 16.51
+	Hs
		1317493 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI54_HUMAN (23-447): 1.48e-60: 209: 21.99
+	Hs
		734819 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI23_HUMAN (18-401): 1.28e-56: 204: 21.60
+	Hs
		734581 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI23_HUMAN (18-401): 1.28e-56: 204: 21.60
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI39_HUMAN (129-519): 4.1e-47: 176: 12.77
+	Hs
		919720 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TIF1B_HUMAN (25-394): 1.78e-43: 170: 16.36
+	Hs
		919712 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI26_HUMAN (20-436): 2.96e-30: 127: 9.98
+	Hs
		1313765 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI62_HUMAN (26-498): 8.72e-28: 119: 13.60
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI27_HUMAN (22-388): 9.56e-17: 85.9: 12.34
+	Hs
		536779 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI27_HUMAN (22-388): 9.56e-17: 85.9: 12.34
+	Hs
		584923 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RO52_HUMAN (29-134): 4.52e-10: 64.8: 14.29