Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: KIF2C (Q99661)
Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK)
Gene: KIF2C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 24931513, 29764989
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 603
Hs

1 725
+ Hs
+ Hs
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+ Ce
+ Dm
+ Hs
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+ Ce
+ Ce
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+ Hs
+ Hs
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+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 11Aug2025