HitPredict

Interactor 1: MK01 (P63085)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27507650, 28671696, 19455133
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0019901 - protein kinase binding GO:0032839 - dendrite cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 358 Mm			1 724
+	Rn
		677771 MK01_RAT (1-358): 3.67e-159: 451: 100.00		DLG4_RAT (1-724): 0: 671: 99.45
+	Mm
		1143328 MK03_MOUSE (13-355): 3.86e-153: 437: 88.34		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Rn
		926488 MK01_RAT (1-358): 3.67e-159: 451: 100.00		DLG3_RAT (20-724): 0: 585: 63.94
+	Mm
		140069 MK12_MOUSE (1-357): 4.56e-141: 406: 40.77		DLG1_MOUSE (8-724): 0: 577: 68.93
+	Rn
		1144013 MK12_RAT (1-357): 1.02e-141: 407: 41.32		DLG1_RAT (8-724): 0: 564: 66.98
+	Mm
		814054 MK14_MOUSE (16-354): 7.69e-111: 329: 48.97		DLG1_MOUSE (8-724): 0: 577: 68.93
+	Hs
		658937 MK01_HUMAN (9-358): 5.56e-158: 448: 99.71		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		647575 MK03_HUMAN (3-356): 7.99e-154: 439: 85.88		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		658938 MK01_HUMAN (9-358): 5.56e-158: 448: 99.71		MPP2_HUMAN (2-189): 1.25e-16: 85.9: 15.71