HitPredict

Interactor 1: SHAN1 (D3YZU1)
SH3 and multiple ankyrin repeat domains protein 1 (Shank1)
Gene: Shank1

Interactor 2: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 27507650, 28706196, 28671696, 36417873
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0017124 - SH3 domain binding
GO:0050804 - modulation of chemical synaptic transmission
GO:0098978 - glutamatergic synapse
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2167
Mm

1 1340
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Last updated: 11Aug2025