HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 28514442, 25959826, 33961781, 16713569, 29844126, 18337722
Identification Methods affinity chromatography technology, two hybrid, molecular sieving, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
and 7 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 815
Hs

1 2517
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025