HitPredict

Interactor 1: D3ZV15 (D3ZV15)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl

Interactor 2: M3K11 (Q66HA1)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3)
Gene: Map3k11

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19546888
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 894 Rn			1 850
+	Hs
		651345 CBL_HUMAN (1-851): 0: 848: 91.56		M3K11_HUMAN (1-850): 0: 652: 92.71
+	Mm
		362435 CBL_MOUSE (1-868): 0: 868: 97.81		ABL1_MOUSE (21-809): 9.73e-122: 396: 20.64
+	Hs
		362162 CBL_HUMAN (1-851): 0: 848: 91.56		ABL1_HUMAN (21-850): 7.73e-124: 402: 19.09
+	Hs
		651206 CBL_HUMAN (1-851): 0: 848: 91.56		ABL2_HUMAN (25-773): 1.57e-116: 383: 21.24
+	Hs
		557095 CBL_HUMAN (1-851): 0: 848: 91.56		SRC_HUMAN (20-392): 1.2e-119: 374: 27.72
+	Hs
		462986 CBL_HUMAN (1-851): 0: 848: 91.56		YES_HUMAN (20-392): 2.14e-118: 371: 28.50
+	Hs
		362274 CBLB_HUMAN (23-726): 0: 729: 55.83		ABL1_HUMAN (21-850): 7.73e-124: 402: 19.09
+	Hs
		557275 CBLB_HUMAN (23-726): 0: 729: 55.83		SRC_HUMAN (20-392): 1.2e-119: 374: 27.72
+	Hs
		463078 CBLB_HUMAN (23-726): 0: 729: 55.83		YES_HUMAN (20-392): 2.14e-118: 371: 28.50
+	Hs
		557519 CBLC_HUMAN (42-498): 0: 625: 43.52		SRC_HUMAN (20-392): 1.2e-119: 374: 27.72
+	Hs
		463259 CBLC_HUMAN (42-498): 0: 625: 43.52		YES_HUMAN (20-392): 2.14e-118: 371: 28.50
+	Hs
		362149 MUC1_HUMAN (415-815): 2.56e-14: 79.6: 10.73		ABL1_HUMAN (21-850): 7.73e-124: 402: 19.09
+	Hs
		557066 MUC1_HUMAN (415-815): 2.56e-14: 79.6: 10.73		SRC_HUMAN (20-392): 1.2e-119: 374: 27.72