HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: CAP1 (Q01518)
Adenylyl cyclase-associated protein 1 (CAP 1)
Gene: CAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CAP_C
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0007015 - actin filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 475
+	Hs
		891700 ACTB_HUMAN (4-377): 0: 599: 94.12		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		929826 ACTG_HUMAN (4-377): 0: 599: 94.39		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		932956 ACTS_HUMAN (1-377): 0: 599: 98.94		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		915363 ACTA_HUMAN (1-377): 0: 596: 98.41		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		768462 ACTB_HUMAN (4-377): 0: 599: 94.12		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		768466 ACTG_HUMAN (4-377): 0: 599: 94.39		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		768467 ACTC_HUMAN (1-377): 0: 599: 100.00		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		768468 ACTS_HUMAN (1-377): 0: 599: 98.94		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		768474 Q1KLZ0_HUMAN (4-377): 0: 599: 94.12		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		768465 ACTA_HUMAN (1-377): 0: 596: 98.41		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Dm
		361193 ACT4_DROME (1-377): 0: 649: 92.57		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		501500 ACT1_DROME (1-377): 0: 598: 94.43		Q7KN55_DROME (4-475): 0: 552: 42.89
+	Dm
		501544 ACT1_DROME (1-377): 0: 598: 94.43		Q9VPX7_DROME (43-475): 0: 552: 46.79
+	Dm
		361155 ACT2_DROME (1-377): 0: 596: 94.16		Q9VPX7_DROME (43-475): 0: 552: 46.79
+	Sp
		501577 ACT_SCHPO (4-377): 0: 645: 89.04		CAP_SCHPO (14-473): 8.25e-175: 503: 32.92
+	Dm
		501456 ACT5_DROME (1-377): 0: 598: 93.10		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		501543 ACT1_DROME (1-377): 0: 598: 94.43		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		361154 ACT2_DROME (1-377): 0: 596: 94.16		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		862578 ACT3_DROME (1-377): 0: 595: 92.57		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		950127 ACT6_DROME (1-377): 0: 594: 92.84		Q9VPX6_DROME (4-475): 0: 530: 42.89