HitPredict

Interactor 1: E9PW37 (E9PW37)
RAS protein activator like 2
Gene: Rasal2

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28706196
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005096 - GTPase activator activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1286 Mm			1 1186
+	Mm
		1012208 Q0VAV5_MOUSE (19-1286): 0: 1250: 99.92		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112542 DAB2P_MOUSE (152-1285): 0: 938: 56.74		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		99969 SYGP1_MOUSE (62-1285): 0: 855: 42.83		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Hs
		1355995 NGAP_HUMAN (152-1286): 0: 1046: 97.45		AGAP1_HUMAN (384-1145): 0: 713: 53.70
+	Mm
		93411 SYGP1_MOUSE (62-1285): 0: 855: 42.83		E9Q3K3_MOUSE (80-1145): 0: 783: 43.63
+	Mm
		100045 SYGP1_MOUSE (62-1285): 0: 855: 42.83		AGAP1_MOUSE (384-1145): 0: 710: 53.70
+	Mm
		99872 F6QQP6_MOUSE (479-1256): 1.2e-164: 510: 49.94		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112670 RASL1_MOUSE (224-919): 2.09e-159: 499: 18.09		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		99881 SYGP1_MOUSE (62-1285): 0: 855: 42.83		F8VQE9_MOUSE (384-1150): 0: 660: 51.54
+	Mm
		1112565 IQGA2_MOUSE (288-899): 4.69e-137: 458: 14.47		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112651 IQGA1_MOUSE (288-909): 4.98e-131: 443: 12.39		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		980214 NF1_MOUSE (440-728): 7.55e-88: 317: 28.13		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		100015 SYGP1_MOUSE (62-1285): 0: 855: 42.83		ASAP2_MOUSE (690-1168): 1.01e-99: 341: 21.08
+	Mm
		88329 SYGP1_MOUSE (62-1285): 0: 855: 42.83		D3YX85_MOUSE (690-1168): 1.11e-97: 335: 21.08
+	Mm
		100001 SYGP1_MOUSE (62-1285): 0: 855: 42.83		GIT1_MOUSE (932-1139): 6.25e-72: 258: 32.88
+	Hs
		598546 NF1_HUMAN (440-728): 5.18e-88: 318: 27.81		AGAP1_HUMAN (384-1145): 0: 713: 53.70
+	Hs
		809252 IQGA1_HUMAN (288-909): 1.46e-129: 439: 12.39		RAP1A_HUMAN (398-567): 1.81e-70: 235: 23.03
+	Hs
		596403 RASA1_HUMAN (238-770): 3.01e-141: 458: 26.27		ACAP2_HUMAN (634-1166): 2.28e-51: 197: 13.44
+	Sc
		533758 BUD2_YEAST (250-761): 1.87e-111: 378: 23.01		RSR1_YEAST (398-656): 8.23e-79: 262: 17.91