Protein: SEM1
26S proteasome complex subunit SEM1

Gene: SEM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: O94742

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0000724 - double-strand break repair via homologous recombination
GO:0005829 - cytosol
GO:0006406 - mRNA export from nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

294162

RPN7
26S proteasome regulatory subunit RPN7

8

1

Small-scale

0.965

High

294167

RPN5
26S proteasome regulatory subunit RPN5

7

1

Small-scale

0.956

High

294139

CSN12
Cop9 signalosome complex subunit 12

6

1

Small-scale

0.942

High

294136

SAC3
Nuclear mRNA export protein SAC3

6

1

Small-scale

0.932

High

294164

THP1
Nuclear mRNA export protein THP1

5

2

Small-scale

0.916

High

294127

RPN3
26S proteasome regulatory subunit RPN3

7

0

Small-scale

0.907

High

294160

RPN9
26S proteasome regulatory subunit RPN9

5

0

Small-scale

0.865

High

294168

RPN6
26S proteasome regulatory subunit RPN6

4

0

Small-scale

0.836

High

294166

THP3
Protein THP3

3

1

Small-scale

0.770

High

294133

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

14

1

Small-scale

0.757

High

294120

RPN1
26S proteasome regulatory subunit RPN1

6

1

Small-scale

0.729

High

294112

PRS7
26S proteasome regulatory subunit 7 homolog

5

2

Small-scale

0.709

High

294106

RPN2
26S proteasome regulatory subunit RPN2

5

1

Small-scale

0.706

High

294149

PRS10
26S proteasome subunit RPT4

5

2

Small-scale

0.706

High

294154

PRS8
26S proteasome regulatory subunit 8 homolog

5

2

Small-scale

0.706

High

294111

PRS6B
26S proteasome regulatory subunit 6B homolog

4

1

Small-scale

0.683

High

294130

PRS4
26S proteasome regulatory subunit 4 homolog

4

2

Small-scale

0.683

High

294105

RPN12
26S proteasome regulatory subunit RPN12

5

0

Small-scale

0.679

High

294110

PRS6A
26S proteasome regulatory subunit 6A

5

0

Small-scale

0.676

High

294122

RPN10
26S proteasome regulatory subunit RPN10

4

0

Small-scale

0.653

High

294165

RPN8
26S proteasome regulatory subunit RPN8

4

0

Small-scale

0.653

High

294093

PSB4
Proteasome subunit beta type-4

3

2

Small-scale

0.650

High

294117

HSM3
DNA mismatch repair protein HSM3

4

0

Small-scale

0.648

High

294142

PSD10
Probable 26S proteasome regulatory subunit p28

3

0

High-throughput

0.634

High

294170

SUS1
Transcription and mRNA export factor SUS1

3

0

Small-scale

0.628

High

141809

RPN13
26S proteasome regulatory subunit RPN13

3

0

Small-scale

0.622

High

294095

PSA2
Proteasome subunit alpha type-2

2

1

High-throughput

0.584

High

294109

RAD23
UV excision repair protein RAD23

2

0

High-throughput

0.576

High

294134

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

2

0

High-throughput

0.576

High

294148

RPN14
26S proteasome regulatory subunit RPN14

2

0

High-throughput

0.559

High

294116

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.518

High

294153

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.515

High

294081

CDC31
Cell division control protein 31

1

0

High-throughput

0.493

High

294089

SEC18
Vesicular-fusion protein SEC18

1

0

High-throughput

0.493

High

294090

DDR48
Stress protein DDR48

1

0

High-throughput

0.493

High

294115

SQT1
Ribosome assembly protein SQT1

1

0

High-throughput

0.493

High

294125

NPT1
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.493

High

294137

TRS85
Trafficking protein particle complex III-specific subunit 85

1

0

High-throughput

0.493

High

294082

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

294088

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

294096

PSB6
Proteasome subunit beta type-6

1

2

High-throughput

0.479

High

294097

PSB2
Proteasome subunit beta type-2

1

1

High-throughput

0.479

High

294100

PSB3
Proteasome subunit beta type-3

1

1

High-throughput

0.479

High

294118

PSB1
Proteasome subunit beta type-1

1

2

High-throughput

0.479

High

294092

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

294094

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.458

High

294119

ECM29
Proteasome component ECM29

1

0

High-throughput

0.458

High

294129

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.458

High

294131

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

294143

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

Small-scale

0.458

High

294146

INO80
Chromatin-remodeling ATPase INO80

1

0

Small-scale

0.458

High

294151

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

High-throughput

0.458

High

294156

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

294157

RPN4
Protein RPN4

1

0

Small-scale

0.458

High

294161

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

294083

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

294084

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

294085

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

294098

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

294101

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

294107

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

294108

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

294124

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

294128

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

294132

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.445

High

294150

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

294087

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

294121

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

294126

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

294163

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.426

High

294099

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

294135

ERJ5
ER-localized J domain-containing protein 5

1

3

High-throughput

0.407

High

294141

HLJ1
Protein HLJ1

1

1

High-throughput

0.407

High

294144

CWC23
Pre-mRNA-splicing factor CWC23

1

1

High-throughput

0.407

High

294091

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.269

Low

294102

DPO4
DNA polymerase IV

1

0

High-throughput

0.269

Low

294114

TOD6
Transcriptional regulatory protein TOD6

1

0

High-throughput

0.269

Low

294140

TCB2
Tricalbin-2

1

0

High-throughput

0.269

Low

294145

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.269

Low

294152

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

0

High-throughput

0.269

Low

294169

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.251

Low

294103

PRR1
Serine/threonine-protein kinase PRR1

1

0

High-throughput

0.249

Low

294104

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

294155

ADA2
Transcriptional adapter 2

1

0

Small-scale

0.249

Low

294158

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

294159

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

294086

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

294113

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

294123

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

294138

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

294147

JAC1
J-type co-chaperone JAC1, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024