HitPredict

Interactor 1: E9PZP8 (E9PZP8)
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Gene: Herc1

Interactor 2: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4859 Mm			1 734
+	Hs
		475811 HERC1_HUMAN (1-4859): 0: 6531: 97.29		UBC_HUMAN (77-724): 0: 790: 97.22
+	Rn
		1140970 Q5YB86_RAT (4359-4841): 1.23e-159: 521: 20.69		UBC_RAT (1-724): 0: 898: 97.51
+	Hs
		125113 WWP2_HUMAN (4347-4841): 3.83e-165: 537: 21.71		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476403 SMUF2_HUMAN (4354-4841): 2.98e-163: 527: 22.45		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476229 NED4L_HUMAN (4353-4839): 7.07e-160: 526: 20.32		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		475470 NEDD4_HUMAN (4356-4839): 3.7e-155: 523: 20.48		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476350 WWP1_HUMAN (4359-4841): 1.02e-157: 518: 21.02		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476205 ITCH_HUMAN (4359-4841): 2.91e-157: 516: 20.69		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476414 SMUF1_HUMAN (4370-4841): 1.13e-157: 511: 21.53		UBC_HUMAN (77-724): 0: 790: 97.22
+	Sc
		477293 RSP5_YEAST (4361-4841): 7.29e-156: 508: 20.04		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	Sp
		143368 PTR1_SCHPO (4389-4839): 1.05e-139: 496: 23.53		UBI4P_SCHPO (381-724): 2.59e-136: 408: 90.99
+	At
		1091758 UPL1_ARATH (4406-4839): 1.01e-136: 487: 23.65		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091762 UPL2_ARATH (4406-4839): 7.64e-136: 484: 23.65		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Hs
		125347 WWP2_HUMAN (4347-4841): 3.83e-165: 537: 21.71		RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00
+	Hs
		924156 WWP1_HUMAN (4359-4841): 1.02e-157: 518: 21.02		RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00
+	Hs
		125112 WWP2_HUMAN (4347-4841): 3.83e-165: 537: 21.71		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		475196 SMUF2_HUMAN (4354-4841): 2.98e-163: 527: 22.45		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		397834 NEDD4_HUMAN (4356-4839): 3.7e-155: 523: 20.48		ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69
+	Hs
		474953 NEDD4_HUMAN (4356-4839): 3.7e-155: 523: 20.48		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		475140 ITCH_HUMAN (4359-4841): 2.91e-157: 516: 20.69		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70