HitPredict

Interactor 1: CENPF (P49454)
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)
Gene: CENPF

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35384245, 14968112
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3114 Hs			1 1620
+	Hs
		773080 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1132358 GOGB1_HUMAN (2316-3089): 9.82e-17: 90.1: 11.78		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1117526 SPTN1_HUMAN (4-1546): 3.69e-13: 78.5: 10.46		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		773304 MYH10_HUMAN (1-419): 1.41e-12: 76.6: 11.19		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		711891 GOGB1_HUMAN (2316-3089): 9.82e-17: 90.1: 11.78		LTK_HUMAN (606-1458): 2.7e-178: 559: 53.24
+	Hs
		710604 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		EPHA3_HUMAN (943-1427): 1.05e-119: 403: 25.05
+	Hs
		650377 AKAP9_HUMAN (1201-3083): 1.68e-32: 142: 9.38		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		840958 EEA1_HUMAN (1949-2674): 4.01e-11: 71.6: 21.32		ABL2_HUMAN (1103-1526): 1.43e-118: 405: 32.47
+	Hs
		650169 EEA1_HUMAN (1949-2674): 4.01e-11: 71.6: 21.32		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		439751 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465525 EEA1_HUMAN (1949-2674): 4.01e-11: 71.6: 21.32		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		411474 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		456106 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		FES_HUMAN (1114-1384): 4.52e-59: 222: 42.80
+	Hs
		541498 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		411900 SPTN1_HUMAN (4-1546): 3.69e-13: 78.5: 10.46		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411475 MYH10_HUMAN (1-419): 1.41e-12: 76.6: 11.19		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411300 DESP_HUMAN (282-945): 7.12e-11: 70.9: 19.30		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412892 MRCKB_HUMAN (2279-2818): 8.81e-11: 70.5: 21.73		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412031 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		456090 DESP_HUMAN (282-945): 7.12e-11: 70.9: 19.30		FES_HUMAN (1114-1384): 4.52e-59: 222: 42.80