HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	15960974, 11882902, 26527279, 29568061, 36089195, 15136563, 15100215, 16622419, 11242053, 16415788, 20871592
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology, proximity labelling technology, unspecified method, surface plasmon resonance, far western blotting, protein array
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 185
+	Hs
		934721 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		1027017 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Mm
		935445 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		CBX1_MOUSE (1-185): 2.21e-62: 193: 100.00
+	Hs
		949795 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		800341 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		800397 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		203659 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		327837 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX7_HUMAN (12-114): 5.3e-30: 112: 27.18
+	Hs
		327844 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX7_HUMAN (12-114): 5.3e-30: 112: 27.18
+	Hs
		935237 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV92_HUMAN (13-121): 2.75e-28: 110: 28.18
+	Hs
		316000 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		934768 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		935387 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		1059154 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		316040 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		123231 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		123254 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		935259 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		934987 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CDYL2_HUMAN (17-122): 5.86e-24: 99.4: 28.44
+	Hs
		1086221 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CDYL2_HUMAN (17-122): 5.86e-24: 99.4: 28.44