HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: KMT5A (Q9NQR1)
N-lysine methyltransferase KMT5A (EC 2.1.1.-) (H4-K20-HMTase KMT5A) (Histone-lysine N-methyltransferase KMT5A) (EC 2.1.1.361) (Lysine N-methyltransferase 5A) (Lysine-specific methylase 5A) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8)
Gene: KMT5A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	24981860, 36089195
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 393
+	Hs
		934804 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		EZH2_HUMAN (134-386): 6.9e-64: 219: 18.25
+	Hs
		1079993 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		EZH2_HUMAN (134-386): 6.9e-64: 219: 18.25
+	Hs
		935129 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		NSD1_HUMAN (109-378): 5.09e-62: 218: 21.58
+	Hs
		935204 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SETD2_HUMAN (98-390): 4.77e-62: 218: 15.41
+	Hs
		935237 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV92_HUMAN (117-392): 1.41e-66: 218: 22.11
+	Hs
		935126 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		EHMT2_HUMAN (135-387): 8.74e-62: 217: 20.07
+	Hs
		1086279 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		EHMT2_HUMAN (135-387): 8.74e-62: 217: 20.07
+	Hs
		935205 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		NSD3_HUMAN (129-378): 4.68e-61: 215: 18.61
+	Hs
		935276 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		ASH1L_HUMAN (28-390): 8.65e-61: 214: 16.13
+	Hs
		331780 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		NSD2_HUMAN (134-378): 2.27e-60: 213: 22.13
+	Hs
		331823 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		NSD2_HUMAN (134-378): 2.27e-60: 213: 22.13
+	At
		886465 H33_ARATH (1-136): 7.67e-62: 187: 96.32		ATXR5_ARATH (36-388): 1.06e-63: 210: 18.59
+	Hs
		934681 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KMT2A_HUMAN (170-390): 6.44e-58: 206: 24.89
+	Hs
		935251 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		EHMT1_HUMAN (102-388): 3.46e-58: 206: 17.16
+	Hs
		975268 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KMT2A_HUMAN (170-390): 6.44e-58: 206: 24.89
+	Hs
		203659 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV91_HUMAN (134-379): 5.5e-60: 201: 20.08
+	Hs
		935368 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KMT2B_HUMAN (171-390): 1.16e-49: 182: 25.46
+	Hs
		935374 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SET1B_HUMAN (269-377): 1.87e-36: 143: 28.44
+	Hs
		165661 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SET1A_HUMAN (201-377): 4.55e-35: 139: 23.50
+	Hs
		934780 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SETB1_HUMAN (205-300): 8.9e-16: 81.4: 14.56