HitPredict

Interactor 1: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Interactor 2: JDP2 (P97875)
Jun dimerization protein 2
Gene: JDP2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22989952
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 488 Mm			1 163
+	Mm
		450547 HDAC2_MOUSE (1-488): 0: 706: 100.00		JUNB_MOUSE (9-141): 1.57e-23: 96: 22.30
+	Hs
		345504 HDAC2_HUMAN (1-488): 0: 707: 99.39		FOS_HUMAN (17-163): 4.88e-22: 92.6: 29.59
+	Mm
		936396 HDAC2_MOUSE (1-488): 0: 706: 100.00		ATF3_MOUSE (82-162): 8.42e-24: 93.4: 66.67
+	Mm
		526735 HDAC2_MOUSE (1-488): 0: 706: 100.00		FOSB_MOUSE (82-149): 4.77e-21: 89.1: 41.18
+	Mm
		140255 HDAC1_MOUSE (1-446): 0: 647: 89.46		JDP2_MOUSE (1-163): 6.45e-33: 116: 100.00
+	Hs
		1038579 HDAC1_HUMAN (1-446): 0: 643: 89.24		JDP2_HUMAN (1-163): 3.12e-33: 117: 96.32
+	Dm
		599218 HDAC1_DROME (5-472): 0: 654: 77.71		FOSLA_DROME (13-150): 3.94e-22: 93.7: 26.62
+	Mm
		140216 HDAC1_MOUSE (1-446): 0: 647: 89.46		JUNB_MOUSE (9-141): 1.57e-23: 96: 22.30
+	Hs
		548245 HDAC1_HUMAN (1-446): 0: 643: 89.24		FOSL1_HUMAN (46-143): 5.6e-21: 87.9: 41.84
+	Hs
		579204 HDAC1_HUMAN (1-446): 0: 643: 89.24		ATF3_HUMAN (82-162): 1.23e-20: 85.2: 66.67
+	Ce
		105173 HDA1_CAEEL (7-456): 0: 596: 64.02		FOS1_CAEEL (2-153): 3.56e-21: 90.6: 23.27
+	Mm
		957049 Q9JM08_MOUSE (10-431): 0: 569: 57.78		JDP2_MOUSE (1-163): 6.45e-33: 116: 100.00
+	Mm
		1141349 Q9JM08_MOUSE (10-431): 0: 569: 57.78		ATF3_MOUSE (82-162): 8.42e-24: 93.4: 66.67
+	Hs
		177189 HDAC3_HUMAN (10-431): 0: 575: 58.02		ATF3_HUMAN (82-162): 1.23e-20: 85.2: 66.67
+	Sp
		223487 CLR6_SCHPO (6-406): 0: 564: 60.64		ATF1_SCHPO (18-151): 3.88e-22: 93.7: 25.37
+	Hs
		1264525 HDAC6_HUMAN (11-363): 7.53e-102: 332: 24.04		JDP2_HUMAN (1-163): 3.12e-33: 117: 96.32
+	Hs
		579232 HDAC6_HUMAN (11-363): 7.53e-102: 332: 24.04		ATF3_HUMAN (82-162): 1.23e-20: 85.2: 66.67